1st ESRS Sleep Science School "Neural Networks in Sleep"

The Sleep Science School is a new ESRS initiative aimed at gathering early career sleep scientists around different fundamental topics, allowing them to gain knowledge, share their work and experience, meet experienced researchers, develop opportunities and create novel networks of excellence.

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The focus of the first edition of the ESRS Sleep Science School will be "Neural Networks in Sleep". It will be held in Frejus, a city located on the Mediterranean sea (France), 16 - 21 October 2017. Pierre-Hervé Luppi and Philippe Peigneux will coordinate this edition.

Both animal and human research will be addressed. The programme will include communications by international sleep experts on specific topics (see below) but also workshop interactive sessions aimed at writing research grants and proposals and stimulate in-depth exchanges between young and experienced researchers. The faculty members will be present during the entire week and available for theoretical and practical discussions with young researchers.

Neural networks in sleep refer to the neurophysiological and neuroanatomical organization of populations of neurons responsible for generating the sleep-waking cycle or implicated in the functions of sleep. It can be investigated both in human and animal using classical approaches such as electrophysiology and neuroanatomy but also new ones like optogenetic or MEG. All these methods are necessary for an in-depth understanding of the mechanisms regulating sleep and to determine how these mechanisms are potentially modulated by daytime experience and/or disrupted in pathological conditions, and subserve or cohere with crucial cognitive functions.

40 participants have been accepted to the ESRS Sleep Science School.

Philippe Peigneux and Pierre-Hervé Luppi                    Lino Nobili
Organizers of the School                                               ESRS Secretary

 

Monday, 16.10.2017: Arrival and get-together

19:30 – 22:00 Get-together session: Buffet dinner and poster hanging/discussion

Tuesday, 17.10.2017: Day 1 

07:45 - 09:00
Breakfast
09:00 - 10:00 General program overview, participants' and faculty presentation, constitution of small groups for workshop activities
10:00 - 11:30 Lecture 1: Alain Destexhe
11:30 – 12:30     Oral Poster Presentation 1 (12 minutes/poster; n = 5 posters)
12:30 – 15:00 Lunch and Social (free time, on site games and sport activities)
14:45 Coffee break
15:00 – 16:00     Oral Poster Presentation 2
16:00 – 17:30 Lecture 2: Vlad Vyazovskiy
17:30 Coffee break + light food
18:00 – 19:00     Oral Poster Presentation 3
19:00 – 20:00 Debate session I (collegial)
20:00 – 21:00 Dinner
21:00 – 22:00 Night Sleep Game : to be organized by all participants and faculty

Wednesday, 18.10.2017: Day 2 

07:45 - 09:00 Breakfast and group picture
09:00 – 10:30 Lecture 3: Anita Lüthi
10:30 – 11:00 Lecture "How to write a successful grant?"
11:00 – 12:00 Development of multidisciplinary scientific grants to be presented Friday (5 members/groups, with partial moderation by faculty)
12:00 – 16:00
Pique-Nique + Trekking on the sea shore by small groups with informal discussion with the faculty
16:00 Coffee break + light food
16:30 – 17:30 Oral Poster Presentation 4
17:30 – 19:00 Lecture 4: Patricia Bonnavion
19:00 – 20:00 Oral Poster Presentation 5
20:00 – 21:00 Dinner
21:00 - 22:00 Debate session II (collegial)

Thursday, 19.10.2017: Day 3 

07:4509:00 Breakfast
09:00 – 10:30 Lecture 5: Hans-Peter Landolt
10:30 – 11:30 Oral Poster Presentation 6
11:30 – 12:30 Workshop activity preparing project/grant - continued
12:30 – 15:00 Lunch and Social (free time, games and sport activities)
14:45 Coffee break
15:00 – 16:00 Oral Poster Presentation 7
16:00 – 17:30 Lecture 6: Pierre-Hervé Luppi
17:30 Coffee break + light food
18:00 – 19:00 Oral Poster Presentation 8
19:00 – 20:00 Workshop activity preparing project/grant - continued
20:00 – 21:00 Dinner

Friday, 20.10.2017: Day 4  

07:45 - 09:00 Breakfast
09:00 – 10:30 Lecture 7: Victor Spoormaker
10:30 – 11:00 Open discussion on how to find postdoc, next steps, career planning
11:00 – 12.30 Workshop activity preparing project/grant - continued
12:30 – 15:00 Lunch and Social (free time, games and sport activities)
14:45 Coffee break
15:00 – 16:30 Lecture 8: Philippe Peigneux
16:30 – 18:00 Workshop activity - Grants Oral Presentations
18:00 Coffee break + light food
18:30 – 20:00 Workshop activity - Grants Oral Presentations
20:00 – 21:00 Dinner
21:00 – Dance party  

Saturday, 21.10.2017: Departure

07:45 - 09:00Breakfast

 

Debate session I . Sleep and plasticity

de Vivo, L., Bellesi, M., Marshall, W., Bushong, E. A., Ellisman, M. H., Tononi, G., & Cirelli, C. (2017). Ultrastructural evidence for synaptic scaling across the wake/sleep cycle. Science, 355(6324), 507-510.

Durkin, J., & Aton, S. J. (2016). Sleep-Dependent Potentiation in the Visual System Is at Odds with the Synaptic Homeostasis Hypothesis. Sleep, 39(1), 155-159

Debate session II. Is there a reproducibility crisis in sleep research ?

Estimating the reproductibility of psychological science? Open Science Collaboration: http://science.sciencemag.org/content/349/6251/aac4716

Dumas-Mallet, E., Button, K. S., Boraud, T., Gonon, F., & Munafo, M. R. (2017). Low statistical power in biomedical science: a review of three human research domains. R Soc Open Sci, 4(2), 160254.

Lecture 1:
Alain Destexhe – Can we model the neural networks of sleep?

Lecture 2:
Vlad Vyazovskiy - Local and global dynamics of sleep regulation: focus on the use of advanced electrophysiological methods

Lecture 3:
Anita Lüthi - Mechanisms and functions of thalamo-cortical activities: “in vitro" versus “in vivo” approaches

Lecture 4:
Hans-Peter Landolt - Sleep EEG fingerprints, biomarkers and the genetics underlying (human) sleep phenotypes

Lecture 5:
Patricia Bonnavion – A review and critic of the new genetic methods applied to the study of sleep networks

Lecture 6:
Pierre-Hervé Luppi: Which animal models and methods to study paradoxical sleep functions, genesis and pathologies?

Lecture 7:
Victor Spoormaker - fMRI/EEG advantages and pitfalls to study brain networks in sleep and their significance

Lecture 8:
Philippe Peigneux: Can we identify the neural networks subtending sleep-learning and sleep-dependent memory consolidation mechanisms in human?