European Sleep Research Laboratories

Research Laboratory

Klinikum Ingolstadt
Centre of Mental Health

Thomas R. Pollmächer
Krumenauerstr. 25
85049 Ingolstadt Germany

Position Director Phone +49 841 880 2201 Fax +49 841 880 2209 Contact E-Mail Website   Research Domain
  • Clinical
  • Basic Human

  • Sleep and Medical Disorders
  • Sleep and Psychiatry-Personality Disorders
  • Sleep and Body Functions (Cardio-Respiratory, Thermoregulation/Metabolism, Endocrine)
  • Behavioural Sleep Disorders
  • Neurological Sleep Disorders

Laboratory Description The sleep research lab at Klinikum Ingolstadt is closely connected to a 6-bed clinical sleep medicine facility at the same location. Research is focussed on basic human and clinical studies. Major areas are sleep and sleep disorders in psychiatric patients, insomnia, RLS and narcolepsy. The major areas of basic research are metabolic functions and immunoendocrine networks during sleep and waking in healthy people and patients with sleep disorders.

The sleep research lab is attached to the Centre of Mental Health, a 300 bed inpatient facility with a huge outpatient department. The Centre of Mental Health is a teaching hospital of the Ludwig-Maximilians-University Munich. Long-term collaborations are established with the Max Planck Institute of Psychiatry in Munich, the Neurocentro della Svizzera Italiana in Lugano, Karls University at Prague, and Peking University.

The head of the sleep research lab, Thomas Pollmächer, is director of the Centre of Mental Health, deputy Medical Director of Klinikum Ingolstadt and Professor of Psychiatry at the Ludwig-Maximilians-University Munich. He has been president of the ESRS from 2004-2008.

Technical Capabilities and areas of expertise Combined PSG and hormonal measurements facilities
Neuropsychological laboratory,
Metabolic assessments

Additional Descriptors, Keywords Sleep in psychiatric disorders, insomnia, narcolepsy, RLS, sleep and metabolism, sleep and immunoendocrine networks.
Selected Publications in the 5 past years Lattova Z, Keckeis M, Maurovich-Horvat E, Wetter TC, Wilde-Frenz J, Schuld A, Pollmächer T (2011) The stress hormone system in various sleep disorders. J Psychiatr Res. 2011 [Epub ahead of print]

Riemann D, Spiegelhader K, Espie C, Pollmächer T, Léger D, Bassetti C, Someren v E. (2011) Chronic Insomnia Clinical and research challenges - an agenda. Pharmacopsychiatry 44:1-14.

Keckeis M, Lattova Z, Maurich- Horvat E, Beitinger PA, Birkmann S, Lauer CJ, Wetter TC, Wilde Frenz J, Pollmächer T (2010) Impaired glucose tolerance in sleep disorders. PLoS One. 5: 9444.

Hennings JM, Ising M, Grautoff S, Himmerich H, Pollmächer T, Schaaf L (2010) Glucose tolerance in depressed inpatients under treatment with mirtazapine and in healthy controls. Exp Clin Endocrinol Diabetes. 118: 98-100.

Pollmächer T (2010) Schlafstörungen. In: Möller HJ, Laux G, Kapfhammer HP (Hrsg.) Psychiatrie, Psychotherapie und Psychosomatik. Springer, Heidelberg. 913-954.

Schuld A, Lauer CJ, Pollmächer T (2010) Sleep during antipsychotic treatment. In: Pandi- Perumal SR, Kramer M (Hrsg.): Sleep and mental illness. Cambridge University Press 2010; 289- 294.

Dzaja A, Wehrle R, Landel M, Pollmächer T (2009) Elevated estradiol plasma levels in women with restless legs during pregnancy. Sleep 32: 169-174.

Maurovich-Horvat E, Pollmächer TZ, Sonka K (2008) The effects of sleep and sleep deprivation on metabolic, endocrine and immune parameters. Prague Med Rep. 109:275-285

Pollmächer T, Wetter TC. Schlafstörungen. In: Holsboer F, Gründer G, Benkert O. (Hrsg.) (2008) Handbuch der Psychopharmakotherapie; Springer Medizin Verlag, Heidelberg 997- 995.

Kümpfel T, Schwan M, Pollmächer T, Yassouridis A, Uhr M, Trenkwalder C, Weber F (2007) Time of interferon-beta 1a injection and duration of treatment affect clinical side effects and acute changes of plasma hormone and cytokine levels in multiple sclerosis patients. Mult Scler 13 : 1138-45.

Wehrle R, Kaufmann C, Wetter TC, Holsboer F, Auer DP, Pollmächer T, Czisch M (2007) Functional microstates within human REM sleep: first evidence from fMRI of thalamocortical network specific for phasic REM periods. Eur J Neurosci 25: 863 – 71.

Pollmächer T, Dalal M, Schuld A (2007) Immunoendocrine abnormalities and narcolepsy. Sleep Medicine Clinics 2: 293-302.

Pollmächer T, Beitinger EB, Schuld A. Metabolic abnormalities in human narcolepsy. In: Bassetti CL, Billiard M, Mignot E (Eds.) (2007): Narcolepsy and hypersomnia. Informa Health Care, New York 459 – 465.

Pollmächer T, Dalal M, Schuld A. Immunoendocrine abnormalities in narcolepsy. In: Vgontzas,A.N. (Eds.) (2007): Sleep Medicine Clinics; Saunders, Philadelphia 2: 293 – 302.

Mayer G, Pollmächer T (Hrsg.) (2007) Narkolepsie – Neue Chancen in Diagnostik und Therapie; Georg Thieme Verlag, Stuttgart .

Schuld A. Haack M. Mullington J. Pollmächer T (2007) Changes in sleep and behavior following experimental immune stimulation using bacterial endotoxin in humans. In: S.R. Pandi-Perumal, D.P. Cardinal, G. Chrousos (Eds.): Neuroimmunology of sleep; Springer, New York 227-231.

Current/Completed Grants (past 5 years) Sino-German Science Foundation. Several grants since 2008 (e.g. GZ538 "Sino German Center for Sleep Research" 2009-2012)

Sanofi-Aventis ESRS Research Grant 2010 (awarded to Marietta Keckeis)

Sanofi-Aventis IIT Grant "Metabolic changes in primary insomnia" (awarded to Thomas Pollmächer, 2010/2011)

European Union, "Consequences of sleep restriction" (MCRTN-CT-2004-512362) 2005-2010

Other laboratory Members
Title PhD First Name Christoph Middle Name J. Last Name Lauer Position Head of the Sleep Disorders Center E-Mail  
Title MD First Name Andreas Last Name Schuld Position Consultant psychiatrist E-Mail  
Title MD First Name Steffen Last Name Birkmann Position Psychiatrist E-Mail  
First Name Andrea Last Name Zahl Position Psychologist E-Mail  
Title MD First Name Dusan Last Name Trstensky Position Psychiatrist E-Mail  
Title MD First Name Karel Last Name Sonka Institution Karls University Prag, Czech Repubilc  
Title MD First Name Claudio Last Name Bassetti Institution Neurocentro Della Svizzera Italiana, Lugano, Switzerland  
Title MD First Name Fang Last Name Han Institution University of Peking, China  
Title MD First Name Axel Last Name Steiger Institution Max Planck Institute of Psychiatry, Munich, Germany  
Past Members
Title PhD First Name Renate Last Name Wehrle E-Mail renate.  
Title MD First Name Eszter Last Name Maurovich-Horvath E-Mail