European Sleep Research Laboratories

Cerrahpasa Faculty of Medicine, Department of Neur

Current Announcements It's a traning center of Turkish Sleep Medicine Society (TSMS). Sleep Medicine Training for 6 months is given to doctors before entering the TSMS Sleep Medicine Board examination. 10-12 doctors comes here for this purpose per year.

Istanbul University, Cerrahpasa Faculty of Medicin
Department of Neurology

Derya Karadeniz
34303 Istanbul Turkey

Position Professor Doctor Phone + 90 212 4143163 Fax + 90 212 6329696 Contact E-Mail   Research Domain
  • Clinical

  • Sleep and Medical Disorders
  • Sleep and Ageing
  • Paediatric Sleep Disorders
  • Neurological Sleep Disorders

Laboratory Description There are 6 beds.
Fullnight polysomnography and MSLT or MWT when needed is performed for 4 nights per week in 6 beds. All kind of sleep disorders in all age groups are evaluated. The research area is primary sleep disorders and sleep disorders related to neurological, medical and psychiatric disorders. It's also an outpatient Sleep Disorders clinic. All kinds of sleep disorders are evaluated on three days per week.

Technical Capabilities and areas of expertise Areas of expertise is primary sleep disorders.
Additional Descriptors, Keywords It's the first Sleep Disorders Center in Turkey has being working since 1993. There are more than 20.000 registered sleep disorders patients. It's a reference center in the country.
Selected Publications in the 5 past years Akcali A, Ferini-Strambi L, Kaynak H, KARADENİZ D, Akcali C. Genital restlessness (vulvodynia) events accompanying restless legs syndrome. Sleep Med. 2009 Mar;10(3):395-6.
Göksan B, Gündüz A, KARADENİZ D, Ağan K, Taşcılar FN, Tan F, Purisa S, Haknak H. Morning headache in sleep apnoea: clinical and polysomnographic evaluation and response to nasal continuous positive airway pressure. Cephalalgia. 2009,29; 635-641.
Benbir G, KARADENİZ D. A pilot study of the effects of non-invasive mechanical ventilation on the prognosis of ischemic cerebrovascular events in patients with obstructive sleep apnea syndrome. Neurol Sci. 2012 Aug;33(4):811-8. Epub 2011 Nov 3.
Kutlu A, Işeri P, Selekler M, Benbir G, KARADENİZ D. Cyclic alternating pattern analysis in REM sleep behavior disorder. Sleep Breath. Sleep Breath. 2012 Feb 28. [Epub ahead of print].
Benbir G, KARADENİZ D. Periodic leg movements in sleep in patients with supratentorial cerebral infarction. Acta Neurol Belg. 2012 Mar;112(1):27-32.
Gündüz A, Adatepe NU, Kiziltan ME, KARADENİZ D, Uysal O. Circadian changes in cortical excitability in restless legs syndrome. J Neurol Sci. 2012 May 15;316(1-2):122-5.
Curgunlu A, Döventaş A, KARADENİZ D, Erdinçler DS, Oztürk AK, Karter Y, Yaldıran A, Sipahioğlu F, Beğer T. Prevalence and characteristics of restless legs syndrome (RLS) in the elderly and the relation of serum ferritin levels with disease severity: Hospital-based study from Istanbul, Turkey. Arch Gerontol Geriatr. 2012 Jul;55(1):73-6.

Key Publications of the Laboratory KAYNAK D, Göksan B, Kaynak H, Değirmencioğlu N, Dağlıoğlu S. Is there a link between the severity of sleep-disordered breathing and atherosclerotic disease of the carotid arteries? European Journal of Neurology, 10;487-493, 2003.
KARADENİZ D, Öztürk L, Gözükırmızı E, Kaynak H. The role of mean inspiratory effort on daytime sleepiness. The European Respiratory Journal, 21;688-694, 2003.
Kaynak H, KAYNAK D, Gözükırmızı E, Guilleminault C. The effects of trazodone on sleep in patients treated with stimulant antidepressants. Sleep Medicine, 5; 15-20, 2004.
Kaynak H, KAYNAK D, Öztura I. Does frequency of nocturnal urination reflect the severity of sleep disordered breathing. Journal of Sleep Research, 13 (2);173-176, 2004.
KAYNAK D, Kızıltan G, Kaynak H, Benbir G, Uysal Ö. Sleep and sleepiness in patients with Parkinson’s disease before and after dopaminergic treatment. European Journal of Neurology, 12; 199-207, 2005.
Oztura I, KAYNAK D, Kaynak H. Nocturia in sleep disordered breathing. Sleep Medicine, 7(4);362-367, 2006.
Kaynak H, Altıntas A, KAYNAK D, Uyanık O, Saib S, Agaoglu J, Onder G, Siva A,. Fatigue and sleep disturbance in multiple sclorosis. European Journal of Neurology, 13; 1333-1339, 2006.

Current/Completed Grants (past 5 years) Sleep Expert, April 2013
Other laboratory Members
Title MD First Name Gulcin Last Name Benbir Position Neurologist E-Mail  
Title MD,PhD First Name Murat Last Name Ozgören Position Professor Doctor Institution Dokuz Eylul University, Biophysics Department  
Past Members
Title MD First Name Erbil Last Name Gozukirmizi E-Mail