European Sleep Research Laboratories

Centre of Sleep Medicine, Centre for Epilepsy Surg

Niguarda Hospital
Department of Neuroscience

PhD,MD
Lino Nobili
Piazza Ospedale Maggiore 3,
20162 Milan Italy


Position Chief of the Sleep Lab Phone +390264447323 Fax +390264442868 Contact E-Mail lino.nobili@ospedaleniguarda.it   Research Domain
  • Basic Human
  • Clinical

Keywords
  • Neurological Sleep Disorders
  • Sleep Physiology-Neurophysiology in Human

Laboratory Description 5 recording rooms
Selected Publications in the 5 past years Siclari F, Khatami R, Urbaniok F, Nobili L, Mahowald MW, Schenck CH, Cramer Bornemann MA, Bassetti CL. Violence in sleep.
Brain. 2010 Dec;133:3494-509.

Nobili L, Proserpio P, Rubboli G, Montano N, Didato G, Tassinari CA. Sudden unexpected death in epilepsy (SUDEP) and sleep. Sleep Med Rev. 2010 Oct 14. [Epub ahead of print

Proserpio P, Spreafico C, Didato G, Nobili L, Facchetti D, De Fanti CA, Protti A. Cyclic alternating pattern (CAP)-related cough and sleep-related laryngospasm. Sleep Med. 2010 Feb;11(2):221-3.

Nobili L. Can homemade video recording become more than a screening tool? Sleep. 2009 Dec 1;32(12):1544-5.

Tassinari CA, Cantalupo G, Högl B, Cortelli P, Tassi L, Francione S, Nobili L, Meletti S, Rubboli G, Gardella E.
Rev Neurol (Paris). Neuroethological approach to frontolimbic epileptic seizures and parasomnias: The same central pattern generators for the same behaviours.2009 Oct;165(10):762-8.

Nobili L, Cardinale F, Magliola U, Cicolin A, Didato G, Bramerio M, Fuschillo D, Spreafico R, Mai R, Sartori I, Francione S, Lo Russo G, Castana L, Tassi L, Cossu M. Taylor's focal cortical dysplasia increases the risk of sleep-related epilepsy.
Epilepsia. 2009 Dec;50(12):2599-604.

Didato G, Nobili L. Treatment of narcolepsy.
Expert Rev Neurother. 2009;9(6):897-910.

Terzaghi M, Sartori I, Tassi L, Didato G, Rustioni V, LoRusso G, Manni R, Nobili L. Evidence of dissociated arousal states during NREM parasomnia from an intracerebral neurophysiological study.Sleep. 2009 32(3):409-12.

Moroni F, Nobili L, Curcio G, De Carli F, Tempesta D, Marzano C, De Gennaro L, Mai R, Francione S, Lo Russo G, Ferrara M.
Procedural learning and sleep hippocampal low frequencies in humans. Neuroimage. 2008 Aug 15;42(2):911-8.

Terzaghi M, Sartori I, Mai R, Tassi L, Francione S, Cardinale F, Castana L, Cossu M, LoRusso G, Manni R, Nobili L. Coupling of minor motor events and epileptiform discharges with arousal fluctuations in NFLE. Epilepsia. 2008 Apr;49(4):670-6.

Italian REMS Study Group, Manconi M, Ferini-Strambi L, Filippi M, Bonanni E, Iudice A, Murri L, Gigli GL, Fratticci L, Merlino G, Terzano G, Granella F, Parrino L, Silvestri R, Aricò I, Dattola V, Russo G, Luongo C, Cicolin A, Tribolo A, Cavalla P, Savarese M, Trojano M, Ottaviano S, Cirignotta F, Simioni V, Salvi F, Mondino F, Perla F, Chinaglia G, Zuliani C, Cesnik E, Granieri E, Placidi F, Palmieri MG, Manni R, Terzaghi M, Bergamaschi R, Rocchi R, Ulivelli M, Bartalini S, Ferri R, Lo Fermo S, Ubiali E, Viscardi M, Rottoli M, Nobili L, Protti A, Ferrillo F, Allena M, Mancardi G, Guarnieri B, Londrillo F. Multicenter case-control study on restless legs syndrome in multiple sclerosis: the REMS study. Sleep. 2008 Jul 1;31(7):944-52.

Moroni F, Nobili L, Curcio G, De Carli F, Fratello F, Marzano C, De Gennaro L, Ferrillo F, Cossu M, Francione S, Lo Russo G, Bertini M, Ferrara M. Sleep in the human hippocampus: a stereo-EEG study. PLoS One. 2007 Sep 12;2(9):e867.

Nobili L. Nocturnal frontal lobe epilepsy and non-rapid eye movement sleep parasomnias: differences and similarities.
Sleep Med Rev. 2007 Aug;11(4):251-4.

Ferrillo F, Donadio S, De Carli F, Garbarino S, Nobili L. A model-based approach to homeostatic and ultradian aspects of nocturnal sleep structure in narcolepsy. Sleep. 2007, 1;30(2):157-65.

Terzaghi M, Sartori I, Mai R, Tassi L, Francione S, Cardinale F, Castana L, Cossu M, LoRusso G, Manni R, Nobili L. Sleep-related minor motor events in nocturnal frontal lobe epilepsy.
Epilepsia. 2007 Feb;48(2):335-41.

Nobili L, Francione S, Mai R, Cardinale F, Castana L, Tassi L, Sartori I, Didato G, Citterio A, Colombo N, Galli C, Lo Russo G, Cossu M. Surgical treatment of drug-resistant nocturnal frontal lobe epilepsy. Brain. 2007 Feb;130(Pt 2):561-73.

Key Publications of the Laboratory Nobili L, Proserpio P, Rubboli G, Montano N, Didato G, Tassinari CA. Sudden unexpected death in epilepsy (SUDEP) and sleep. Sleep Med Rev. 2010 Oct 14. [Epub ahead of print

Nobili L, Cardinale F, Magliola U, Cicolin A, Didato G, Bramerio M, Fuschillo D, Spreafico R, Mai R, Sartori I, Francione S, Lo Russo G, Castana L, Tassi L, Cossu M. Taylor's focal cortical dysplasia increases the risk of sleep-related epilepsy.Epilepsia. 2009 Dec;50(12):2599-604.

Terzaghi M, Sartori I, Tassi L, Didato G, Rustioni V, LoRusso G, Manni R, Nobili L. Evidence of dissociated arousal states during NREM parasomnia from an intracerebral neurophysiological study.Sleep. 2009 32(3):409-12.

Moroni F, Nobili L, Curcio G, De Carli F, Tempesta D, Marzano C, De Gennaro L, Mai R, Francione S, Lo Russo G, Ferrara M.
Procedural learning and sleep hippocampal low frequencies in humans. Neuroimage. 2008 Aug 15;42(2):911-8.

Terzaghi M, Sartori I, Mai R, Tassi L, Francione S, Cardinale F, Castana L, Cossu M, LoRusso G, Manni R, Nobili L. Coupling of minor motor events and epileptiform discharges with arousal fluctuations in NFLE. Epilepsia. 2008 Apr;49(4):670-6.

Moroni F, Nobili L, Curcio G, De Carli F, Fratello F, Marzano C, De Gennaro L, Ferrillo F, Cossu M, Francione S, Lo Russo G, Bertini M, Ferrara M. Sleep in the human hippocampus: a stereo-EEG study. PLoS One. 2007 Sep 12;2(9):e867.

Nobili L. Nocturnal frontal lobe epilepsy and non-rapid eye movement sleep parasomnias: differences and similarities.
Sleep Med Rev. 2007 Aug;11(4):251-4.

Ferrillo F, Donadio S, De Carli F, Garbarino S, Nobili L. A model-based approach to homeostatic and ultradian aspects of nocturnal sleep structure in narcolepsy. Sleep. 2007, 1;30(2):157-65.

Terzaghi M, Sartori I, Mai R, Tassi L, Francione S, Cardinale F, Castana L, Cossu M, LoRusso G, Manni R, Nobili L. Sleep-related minor motor events in nocturnal frontal lobe epilepsy.
Epilepsia. 2007 Feb;48(2):335-41.

Nobili L, Francione S, Mai R, Cardinale F, Castana L, Tassi L, Sartori I, Didato G, Citterio A, Colombo N, Galli C, Lo Russo G, Cossu M. Surgical treatment of drug-resistant nocturnal frontal lobe epilepsy. Brain. 2007 Feb;130(Pt 2):561-73.

Nobili L, Sartori I, Terzaghi M, Stefano F, Mai R, Tassi L, Parrino L, Cossu M, Lo Russo G. Relationship of epileptic discharges to arousal instability and periodic leg movements in a case of nocturnal frontal lobe epilepsy: a stereo-EEG study. Sleep. 2006 May 1;29(5):701-4.

Mai R, Sartori I, Francione S, Tassi L, Castana L, Cardinale F, Cossu M, Citterio A, Colombo N, Lo Russo G, Nobili L. Sleep-related hyperkinetic seizures: always a frontal onset? Neurol Sci. 2005 Dec;26 Suppl 3:s220-4.

Nobili L, Sartori I, Terzaghi M, Tassi L, Mai R, Francione S, Cossu M, Cardinale F, Castana L, Lo Russo G.
Intracerebral recordings of minor motor events, paroxysmal arousals and major seizures in nocturnal frontal lobe epilepsy.
Neurol Sci. 2005 Dec;26 Suppl 3:s215-9.

Nobili L, Cossu M, Mai R, Tassi L, Cardinale F, Castana L, Citterio A, Sartori I, Lo Russo G, Francione S.Sleep-related hyperkinetic seizures of temporal lobe origin. Neurology. 2004 Feb 10;62(3):482-5.

Nobili L, Francione S, Mai R, Tassi L, Cardinale F, Castana L, Sartori I, Lo Russo G, Cossu M. Nocturnal frontal lobe epilepsy: intracerebral recordings of paroxysmal motor attacks with increasing complexity. Sleep. 2003 Nov 1;26(7):883-6.

Nobili L, Francione S, Cardinale F, Lo Russo G. Epileptic nocturnal wanderings with a temporal lobe origin: a stereo-electroencephalographic study. Sleep. 2002 Sep 15;25(6):669-71.




 
Other laboratory Members
 
 
Title MD First Name Ivana Last Name Sartori E-Mail Ivana.Sartori@ospedaleniguarda.it  
First Name Andrea Last Name Lanza E-Mail Andrea.Lanza@ospedaleniguarda.it  
Title MD First Name Paola Last Name Proserpio E-Mail Paola.Proserpio@ospedaleniguarda.it  
Collaborations
 
Title MSc First Name Fabrizio Last Name De Carli Position Senior Researcher Institution CNR-IBFM - Section of Genoa, Via de Toni, 5 - 16132 Genova, Italy  
Title MSc,PhD,MD First Name Marcello Last Name Massimini Institution Dipartimento di Scienze Cliniche "Luigi Sacco" , University of Milan, Italy  
First Name Michele Last Name Ferrara Institution Department of Health Sciences, University of L'Aquila, Italy  
Past Members