European Sleep Research Laboratories

Center for Investigation and Research in Sleep

Centre Hospitalier Universitaire Vaudois
CHUV

MD
Raphael Heinzer
Rue du bugnon 46
1011 Lausanne Switzerland


Position Co-Director (with Mehdi TAFTI, PhD) Phone +41 213146748 Fax +41 213146752 Contact E-Mail raphael.heinzer@chuv.ch Website http://www.chuv.ch/sommeil   Research Domain
  • Basic Animal
  • Methodology / Technology
  • Clinical
  • Basic Human

Keywords
  • Pharmacology – Human
  • Paediatric Sleep Disorders
  • Sleep Physiology-Neurophysiology in Animal
  • Sleep Physiology-Neurophysiology in Human
  • Sleep and Body Functions (Cardio-Respiratory, Thermoregulation/Metabolism, Endocrine)
  • Epidemiology of Sleep
  • Sleep and Ageing
  • Pharmacology of Sleep
  • Genetics of Sleep
  • Sleep and Medical Disorders
  • Instrumentation-Methodology
  • Neurological Sleep Disorders

Laboratory Description Multidisciplinary team
Clinical and research

Selected Publications in the 5 past years Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network Study.
Key Publications of the Laboratory Publication list (since 2008)

Unilateral periodic leg movements during wakefulness and sleep after a parietal hemorrhage
Rossetti AO, Heinzer R, Espa F, Tafti M.
Sleep Med. 2008 May;9(4):465-6.

Effects of Trazodone on Arousal Threshold in OSA
Heinzer R, Malhotra A, Jordan A, Dover L, Schory K, White DP
European Respiratory Journal 2008; 31(6):1308-12.

Effect of Expiratory Positive Expiratory Airway Pressure on Sleep Disordered Breathing
Heinzer R, Malhotra A, Jordan A, Dover L, Schory K, White DP
Sleep 2008;31(3):429-32

La persistance d'activités motrices périodiques lors du sommeil paradoxal et les dommages ou blessures corporels.
Lavigne G, Manzini C, Heinzer R.
Neuro-Psy News, 2008, 7, 2, 56-62.

Oximetry alone versus portable polygraphy for sleep apnoea screening before bariatric surgery
Maude Malbois, Michel Suter, Cyril Pellaton, Jean-Frédéric Vodoz, Vittorio Giusti, Raphael Heinzer
Obes Surg. 2010; 20 (3): 326-331

Rapid occurrence of depression following addition of sodium oxybate to modafinil.
Rossetti AO, Heinzer R, Tafti M, Buclin T.
Sleep med 2010; 11: 500

Drops in Pulse Wave Amplitude, a reliable Surrogate of Cortical
Activation in sleep polygraphic recordings ?
Delessert A, Espa, Rossetti AO, Lavigne G, Tafti M, Heinzer R.
Sleep. 2010 Dec 1;33(12):1687-92

Genome-wide association study identifies new HLA Class II variants strongly protective against narcolepsy.
Hyun Hor ,Zoltán Kutalik,Yves Dauvilliers,Armand Valsesia, Gert J. Lammers, Claire E.H.M. Donjacour, Alex Iranzo, Joan Santamaria, Rosa Peraita Adrados, José L. Vicario, Sebastian Overeem, Isabelle Arnulf, Theodorou Ioannis, Poul Jennum, Stine Knudsen, Claudio Bassetti, Johannes Mathis, Michel Lecendreux, Geert Mayer, Peter Geisler, Antonio Benetó, Billiard, Guadalupe Ercilla, Wiillem Verduijn, Frans H.J. Claas, Peter Vollenweider, Gerard Waeber, Dawn M. Waterworth, Vincent Mooser, Raphaël Heinzer, Jacques S. Beckmann, Sven Bergmann, and Mehdi Tafti
Nat Genet. 2010 Sep;42(9):786-9.

Patent foramen ovale and obstructive sleep apnoea: From pathophysiology to diagnosis of a potentially dangerous association
Cyril Pellaton, Raphaël Heinzer, Patrik Michel, Eric Eeckhout
Archives of Cardiovascular Diseases 2011;104(4):242-51

Narcolepsy with cataplexy associated with H1N1 vaccination.
Haba-Rubo J, Rossetti A, Tafti M, Heinzer R.
Rev. Neurol 2011 (Epub ahead of print)

Improvement of migraine headaches in severely obese patients after bariatric surgery (letter)
José Haba-Rubio, Andrea Rossetti, Mehdi Tafti, Raphael Heinzer
Neurology. 2011 Nov 8;77(19):1772-3

Effect of transnasal insufflation on sleep disordered breathing in acute stroke: A preliminary report.
José Haba-Rubio; Daniella Andries ; Vincianne Rey-Bataillard ; Patrik Michel ; Mehdi Tafti, Raphael Heinzer
Sleep and Breathing 2013 Mar;17(1):289-96

Sleep Disorders in Chronic Renal Failure (review)
José Haba-Rubio, Sophie de Seigneux, Raphael Heinzer
Nephrol Ther. 2012 Apr;8(2):74-80

Positional therapy for obstructive sleep apnea: an objective measurement of efficacy and patients’ usage at home.
Raphael Heinzer 1, Cyril Pellaton MD1, Vincianne Rey MD1, Andrea Rossetti MD1, Gianpaolo Lecciso1, José Haba-Rubio MD1, Mehdi Tafti PHD1,2, Gilles Lavigne DMD1,3
Sleep Med. 2012 Apr;13(4):425-8.
Effect of Added Dead Space on Sleep Disordered Breathing at High Altitude
Lovis A, De Riedmatten M, Lecciso G, Andries D, Scherrer U, Wellman A, Sartori C, Heinzer R.
Sleep Medicine 2012 Apr 11. [Epub ahead of print]

Differential effects of sodium oxybate and baclofen on EEG, sleep, neurobehavioral performance, and memory.
Vienne J, Lecciso G, Constantinescu I, Schwartz S, Franken P, Heinzer R*,
Tafti M*. *Equal contribution
Sleep. 2012 Aug 1;35(8):1071-83.

Kleine-Levin syndrome: Functional imaging correlates of hypersomnia and behavioral symptoms.
Haba-Rubio J, Prior JO, Guedj E, Tafti M, Heinzer R, Rossetti AO.
Neurology. 2012 Oct 30;79(18):1927-9.

Effect of transnasal insufflation on sleep disordered breathing in acute stroke: A preliminary report.
José Haba-Rubio; Daniella Andries ; Vincianne Rey-Bataillard ; Patrik Michel ; Mehdi Tafti, Raphael Heinzer
Sleep and Breathing 2013 Mar;17(1):289-96

Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.
Luca G, Haba-Rubio J, Dauvilliers Y, Lammers GJ, Overeem S, Donjacour CE, Mayer G, Javidi S, Iranzo A, Santamaria J, Peraita-Adrados R, Hor H, Kutalik Z, Plazzi G, Poli F, Pizza F, Arnulf I, Lecendreux M, Bassetti C, Mathis J, Heinzer R, Jennum P, Knudsen S, Geisler P, Wierzbicka A, Feketeova E, Pfister C, Khatami R, Baumann C, Tafti M; European Narcolepsy Network (EU-NN).
J Sleep Res. 2013 Mar 18. doi: 10.1111/jsr.12044


 
Other laboratory Members
 
Title PhD First Name Mehdi Last Name Tafti Position Co-Director E-Mail mehdi.tafti@unil.ch  
Title MD First Name José Last Name Haba-Rubio Position Neurologist, somnologist E-Mail jose.haba-rubio@chuv.ch  
Collaborations
 
Past Members